Atlantis Bioscience and Gempharmatech hosted a webinar on genetically modified mouse models and applications, featuring Dr. Han Bingzhou, a scientist at Gempharmatech. Dr. Han shared his insights on the history of genomic editing technology, animal models modification strategies, how knockout and conditional knockout mice are designed and generated, how to validate the efficiency of CRE expression analysis and lineage tracing, the best quality control standards, and high-impact publications where Gempharmatech’s mice were featured.
Genetically modified mouse models are essential tools for biomedical research. They allow scientists to study the effects of specific genes on development, disease, and other biological processes. Dr. Han discussed the different types of genetically modified mice that are available, as well as the advantages and disadvantages of each type.
He also shared his expertise on how to design and generate knockout and conditional knockout mice. Knockout mice lack a specific gene, while conditional knockout mice allow scientists to delete a gene in a specific cell type or at a specific time during development. These types of mice are particularly useful for studying the function of genes that are essential for life.
Dr. Han also discussed the importance of quality control for genetically modified mice. He explained how Gempharmatech ensures that their mice are of the highest quality and meet the needs of researchers.
Finally, Dr. Han highlighted some of the high-impact publications where Gempharmatech’s mice have been featured. These studies have used Gempharmatech’s mice to advance our understanding of cancer, neurological disorders, and other diseases.