Transgenic Mice for in vivo Genome Modification
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We provide transgenic strains which express Cas9 endonuclease and tdTomato fluorescence indicator in a constitutive (T004285) or Cre-dependent (T002249) manner. These strains can be applied with sgRNA-expressing transgenic mouse strains or viral vectors to achieve genome modification in vivo.
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Strain No.
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Strain Name | Strain Type | Description |
|---|---|---|---|
| T004285 | B6-CAG-cas9-tdTomato | Cas9-KI | This strain can be used for genetic function and oncology research after in vivo knockout/knock-in of single or multiple genes. |
| T002249 | Rosa26-CAG-LSL-Cas9-tdTomato | Cas9-KI | This strain can be used for genetic function and oncology research after in vivo knockout/knock-in of single or multiple genes. |
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