Interleukin-4 (rHu IL-4), produced primarily by CD4(+) T cells is an immunomodulatory cytokine, which can inhibit the growth of tumor cells.

IL-4 has been known as a Th2 cytokine and can act on B cells, T cells, and monocytes. IL-4 exhibits antitumor activity in rodent experimental gliomas, which is likely mediated by the actions of IL-4 on a variety of immune cells present in and around the tumor masses. rHu IL-4 produced in E. coli is a single, non-glycosylated polypeptide chain that contains 130 amino acids and has a molecular mass of 15 kDa.

Features and Specifications:

• Custom packaging and sizes available
• Single-use syringe configuration
• Lyophilized or liquid format
• Pharmaceutical grade
• Sterile-filled
• Custom biological activity assays available

Quality Statement

Akron’s cGMP Cytokines are manufactured, tested and released in compliance with relevant cGMP guidelines. USP Chapter ‹1043› “Ancillary materials for cell, gene and tissue-engineered products” has been followed in the design of these products.