Pre-Made AAV Control Vectors
Pre-Made AAV Control Vectors
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Choosing the Right Pre-Made AAV Control Vectors
When designing your gene therapy experiment, selecting the appropriate AAV control is crucial for accurate data interpretation. A well-chosen control can significantly enhance the reliability and validity of your research.
Key Factors to Consider:
-
AAV Serotype:
- Tissue Tropism: Different serotypes exhibit distinct tissue tropisms, influencing gene expression patterns.
- Immune Response: Consider the potential immunogenicity of the serotype, as it can impact vector efficacy and safety.
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Promoter Strength and Specificity:
- Tissue-Specific Promoters: Target gene expression to specific cell types.
- Constitutive Promoters: Drive continuous gene expression.
-
Reporter Gene:
- Fluorescent Proteins: Visualize gene expression patterns in live cells and tissues.
- Luminescent Proteins: Quantify gene expression levels.
Our Pre-Made AAV Control Vectors: A Tailored Solution
Packgene offers a diverse range of pre-made AAV control vectors to meet your specific research needs. Their
Our products are designed to:
- Validate Gene Delivery: Assess the efficiency and specificity of your AAV vectors.
- Monitor Transgene Expression: Track gene expression levels over time.
- Evaluate Immune Responses: Assess the immunogenicity of your AAV vectors.
Packgene Pre-made AAV Control Vector Advantages:
- Wide Serotype and Strand Options: Available in a range of serotypes and both single-stranded and double-stranded formats.
- High Titer: Exceeding 1E+13 GC/ml for efficient gene delivery.
- Versatile Promoters: Choose from a variety of promoters to match your experimental needs.
- Rapid Expression: Double-stranded AAVs offer 6-15 times faster expression.
- Stable and Reliable Performance: Consistent results for reliable data interpretation.
This product is applicable for worldwide delivery.
Need a Custom Control Vector?
If you have specific requirements, our custom vector design and production services can provide tailored solutions to meet your exact needs.
Contact us today to discuss your research goals and explore our range of pre-made and custom AAV control vectors.
Product Specifications
Purified Empty AAV Capsid Particles
Our empty AAV particles created using only essential components for AAV replication provides a versatile tool for a variety of research applications, including:
- Normalizing Transduction Efficiency: Use as a control to normalize transduction efficiency in gene therapy experiments.
- Studying Viral Entry and Trafficking: Investigate the mechanisms of AAV entry and intracellular trafficking.
- Developing Novel AAV-Based Therapeutics: Engineer empty capsids for targeted drug delivery or as immunotherapeutic agents.
These EMP AAV capsid particles are completely empty capsids that are devoid of any genetic material and therapeutic transgene.
| Type | Catalog No. | Promoter and Gene | Serotype | Concentration | QC |
| Empty AAV particles | AAVEC001 | Non | AAV2, AAV5, AAV8, AAV9 | 1E13 VP/mL | Endotoxin by LAL＜10EU/mL Purity by SDS-PAGE Capsid titer by ELISA |
A Comprehensive Range of AAV Control Vectors
Our pre-made AAV control vectors offer a reliable and efficient solution for your gene therapy, gene editing, gene regulation, vaccine development, and drug discovery research. Choose from a variety of serotypes, promoters, and reporter genes to suit your specific research needs.
Popular Control Vector Combinations:
- Serotype 5 (AAV5): A versatile serotype with broad tissue tropism.
- CAG Promoter: A strong, constitutive promoter for ubiquitous gene expression.
- eGFP or mCherry Reporter: Brightly fluorescent proteins for easy visualization.
- Serotype 8 (AAV8): A potent serotype with high transduction efficiency in various tissues.
- CBh Promoter: A strong, constitutive promoter for efficient gene expression.
- Luciferase Reporter: A sensitive reporter for quantitative analysis.
| Type | Catalog No. | Promoter and Gene |
| No reporter AAV | AAV-EA020 | ssAAV.CAG.WPRE.SV40pA |
| AAV-EC020 | scAAV.CAG.WPRE.SV40pA | |
| AAV-EA040 | ssAAV.CMV.WPRE.SV40pA | |
| Fluorescence | AAV-EA021 | ssAAV.CAG.EGFP.WPRE.SV40pA |
| AAV-EC021 | scAAV.CAG.EGFP.WPRE.SV40pA | |
| AAV-EA041 | ssAAV.CMV.EGFP.WPRE.SV40pA | |
| AAV-EC041 | scAAV.CMV.EGFP.WPRE.SV40pA | |
| AAV-EA022 | ssAAV.CAG.mCherry.WPRE.SV40pA | |
| AAV-EC022 | scAAV.CAG.mCherry.WPRE.SV40pA | |
| AAV-EA042 | ssAAV.CMV.mCherry.WPRE.SV40pA | |
| AAV-C-11723 | scAAV.CMV.mCherry.WPRE.SV40pA | |
| AAV-EB041 | ssAAV.CMV.EGFP.PA48 | |
| AAV-EA191 | ssAAV.CBh.EGFP.WPRE.SV40pA | |
| AAV-EA031 | ssAAV.EF1a.EGFP.WPREs.SV40pA | |
| AAV-EA051B | ssAAV.TBG (669p).EGFP.WPRE.SV40pA | |
| AAV-EA101 | ssAAV.hSyn.EGFP.WPREs.SV40pA | |
| AAV-EA171 | ssAAV.hGFAPS.EGFP.WPREs.SV40pA | |
| AAV-EA411 | ssAAV.miniCMV.EGFP.WPRE.SV40pA | |
| AAV-EA011 | ssAAV.EFS.EGFP.WPRE.SV40pA | |
| AAV-EA042 | ssAAV.CMV.mCherry.WPRE.SV40pA | |
| AAV-EA181 | ssAAV.CTNT.ZsGreen.WPRE.SV40pA | |
| AAV-EA591 | ssAAV.UBC.EGFP.WPRE.SV40pA | |
| AAV-EA361 | ssAAV.Tie1.EGFP.WPRE.SV40pA | |
| AAV-EC011 | scAAV.EFS.EGFP.WPRE.SV40pA | |
| AAV-EA611 | ssAAV.mSP-C promoter.EGFP.WPRE.SV40pA | |
| AAV-EA511 | ssAAV.periostin.EGFP.WPRE.SV40pA | |
| AAV-EA501 | ssAAV.Iba1.EGFP.WPRE.SV40pA | |
| AAV-EB361 | ssAAV.Tie1.EGFP.PA48 | |
| AAV-EA621 | ssAAV.mRPE65.EGFP.WPRE.SV40pA | |
| AAV-EA461 | ssAAV.GfaABC1D.EGFP.WPRE.SV40pA | |
| AAV-EA491 | ssAAV.hICAM2.EGFP.WPRE.SV40pA | |
| AAV-EA102 | ssAAV.hSyn.mCherry.WPRE.SV40pA | |
| AAV-EA071 | ssAAV.Rat Insulin.EGFP.WPRE.SV40pA | |
| AAV-EC028 | scAAV.CAG.GLuc.WPRE.SV40pA | |
| AAV-EA441 | ssAAV.EnSM22α.EGFP.WPRE.SV40pA | |
| AAV-EC051V | scAAV.TBG.EGFP.WPRE.SV40pA | |
| AAV-EC101 | scAAV.hSyn.EGFP.WPRE.SV40pA | |
| AAV-EA391B | ssAAV.MBP(1.9kb).EGFP.WPRE.SV40pA | |
| AAV-EA631 | ssAAV.hBEST1.EGFP.WPRE.SV40pA | |
| AAV-EA026 | ssAAV.CAG.EYFP.WPRE.SV40pA | |
| AAV-EA182 | ssAAV.CTNT.EGFP.WPREs.SV40pA | |
| AAV-EA601 | ssAAV.HCRApoE hAAT.EGFP.WPRE.SV40pA | |
| AAV-EA531 | ssAAV.mALB.EGFP.WPRE.SV40pA | |
| AAV-EC181 | scAAV.CTNT.ZsGreen.WPRE.SV40pA | |
| AAV-C-11592 | ssAAV.SMMHC.EGFP.WPRE.SV40pA | |
| AAV-C-11307 | scAAV.miniCMV.mCherry.WPREs.SV40pA | |
| AAV-C-3199 | ssAAV.CAG.EGFP.NLS.WPRE.SV40pA | |
| Luminesence | AAV-EA029 | ssAAV.CAG.Fluc.WPRE.SV40pA |
| AAV-EA043 | ssAAV.CMV.Fluc.WPRE.SV40pA | |
| AAV-EC028 | scAAV.CAG.Gluc.WPRE.SV40pA | |
| shRNA | AAV-XN09 | scAAV.U6.NCshRNA.CMV.EGFP.WPRE |
| AAV-C-10987 | scAAV.U6.NCshRNA-2.CAG.EGFP.WPRE.SV40pA |
Publications
Xu Li, Ningtao Cheng, Danrong Shi, Yutong Li, Chen Li, Miaojin Zhu, Qiao Jin, Zhigang Wu, Linwei Zhu, Yi He, Hangping Yao, Jian Ji,
Sulfated liposome-based artificial cell membrane glycocalyx nanodecoys for coronavirus inactivation by membrane fusion,
Bioactive Materials,
Volume 33,
2024,
Pages 1-13,
ISSN 2452-199X,
Xu, Y., Zhou, Z., Kang, X. et al. Mettl3-mediated mRNA m6A modification controls postnatal liver development by modulating the transcription factor Hnf4a. Nat Commun13, 4555 (2022).
https://doi.org/10.1038/s41467-022-32169-4
https://doi.org/10.1016/j.bioactmat.2023.10.021.
