PE Anti-Human HLA-DR (L243)

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Product Description

The L243 antibody reacts with a member of the human MHC Class II antigens, HLA-DR. The HLA-DR antigen is expressed on B lymphocytes, activated T lymphocytes, activated NK cells, monocytes, macrophages, other antigen presenting cells and progenitor cells. The L243 antibody is specific to an epitope on the alpha subunit of the heterodimeric HLA-DR protein and binds a different epitope than the LN3 antibody clone. It does not cross-react with HLA-DP or HLA-DQ. This antibody is reported to be cross-reactive with non-human primates including Chimpanzee, Cynomolgus, Rhesus and Baboon. Please choose the appropriate format for each application.

Product Details

Name	PE Anti-Human HLA-DR (L243)
Cat. No.	50-9952
Alternative Names
Gene ID	3122
Clone	L243
Isotype	Mouse IgG2a, κ
Reactivity	Human
Cross Reactivity	Chimpanzee, Cynomolgus, Rhesus, Baboon, Squirrel Monkey, African Green Monkey
Format	PE
Application	Flow Cytometry
Citations*	Brodsky FM. 1984. Immunogenetics. 19(3): 179-194. Robbins PA, Evans EL, Ding AH, Warner NL and Brodsky FM. 1987. Human Immunol. 18(4): 301-313. Poulin LF, Reyal Y, Uronen-Hansson H, Schraml BU, Sancho D, Murphy KM, Hakansson UK, Moita LF, Agace WW, Bonnet D and Reis e Sousa C. 2012. Blood. 119(25): 6052-6062. (Flow cytometry) Shio MT, Hassan GS, Shah WA, Nadiri A, El Fakhry Y, Li H and Mourad W. 2014. J Immunol. 192(6): 2543-2550. (Flow cytometry) Bigley V, McGovern N, Milne P, Dickinson R, Pagan S, Cookson S, Haniffa M and Collin M. 2015. J Leukoc Biol. 97(4): 627-634. (Flow cytometry) Goodier MR and Londei M. 2000. J Immunol. 165(1): 139-147. (Depletion) Kalka-Moll WM, Tzianabos AO, Bryant PW, Niemeyer M, Ploegh HL and Kasper DL. 2002. J Immunol. 169(11): 6149-6153. (Blocking)

Application Key:FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.