Primary animal hepatocytes and subcellular liver fractions (Microsomes, Cytosol and S9 fraction) are model systems often used for a variety of in vitro screenings and analyses prior to clinical studies in human and animal health as well as environmental toxicology.

Hepatocytes in suspension are preferable for short-term studies whereas plated hepatocytes are more useful for long-term studies.

COMMON USES

– Metabolism analysis
– Drug development
– Toxicity assessments
– Enzyme activity studies

DOCUMENTATION