Reference Publications

Bano, Reshma et al.

A perspective on the isolation and characterization of extracellular vesicles from different biofluids

RSC advances vol. 11,32 19598-19615.

DOI: 10.1039/d1ra01576a

Article Snippet: “The latest development has been in SEC automation, i.e., automated fraction collector (AFC). A substantial development to the qEV platform, the Izon AFC allows for the fast, precise, automated isolation of EVs.”

Van Dorpe, Sofie et al.

Integrating automated liquid handling in the separation workflow of extracellular vesicles enhances specificity and reproducibility

Journal of nanobiotechnology vol. 21,1 157.

DOI: 10.1186/s12951-023-01917-z

Article Snippet: “Examples include automated fraction collection (AFC), measuring fluid volume by weight and fully integrated microfluidic systems combining immunoaffinity, filtration, centrifugation, and/or asymmetrical flow field-flow fractionation.”

Byappanahalli, A.M., Noren Hooten, N., Vannoy, M. et al.

Mitochondrial DNA and inflammatory proteins are higher in extracellular vesicles from frail individuals

Immun Ageing 20, 6 (2023).

DOI: https://doi.org/10.1186/s12979-023-00330-2

Article Snippet: “EVs were isolated from plasma samples of these participants using size exclusion chromatography (SEC) with an Automatic Fraction Collector (AFC). The AFC facilitates a high-throughput approach for isolation of EVs from larger numbers of samples.”

Mizenko, R.R., Brostoff, T., Rojalin, T. et al.

Tetraspanins are unevenly distributed across single extracellular vesicles and bias sensitivity to multiplexed cancer biomarkers

J Nanobiotechnol 19, 250 (2021).

DOI: https://doi.org/10.1186/s12951-021-00987-1

Aricle Snippet: “Izon 70 nm qEVsingle columns were utilized in the Izon Automatic Fraction Collector (AFC). Columns were rinsed using 0.2 μm-filtered PBS (4 mL).”