Alzheimer’s disease is the most prevalent type of dementia. It is a progressive neurodegenerative disease that begins with memory loss. As the disease advances, symptoms can include problems with language, a decline in social and vocational functioning, executive dysfunction, personality changes, and behavioral issues.

There is no definitive explanation for the pathogenesis of Alzheimer’s disease, and the mainstream ideas include the amyloid beta (Aβ) hypothesis and the tau hypothesis. Only six AD drugs have been approved to date, and these drugs can only delay disease progression or alleviate symptoms.

A suitable animal model is a crucial research tool for Alzheimer’s disease therapeutic development. GemPharmatech has developed two AD models that can be utilized for the screening and safety evaluation of Alzheimer’s disease drugs.