violetFluor™ 450 Anti-Mouse CD11c (N418)

Tinye na ụgbọ ibu

Ihe mgbochi N418 na-emeghachi omume na òké CD11c, nke a makwaara dị ka integrin αalpha X. Nke a 150 kDa cell surface glycoprotein bụ akụkụ nke ezinụlọ nke integrin αreceptors nke na-eme ka adhesion n'etiti ≥ ≥ ≥ sel (cell-cell) na akụkụ nke extracellular matrix (eg fic-cell). Na mgbakwunye, integrin α bụ ndị na-anabata akara ngosi na-arụ ọrụ nke na-ewebata leukocytes na saịtị mkpasu iwe ma na-akwalite ịgbalite cell. Ndị na-anabata integrin zuru oke, na-arụ ọrụ nwere ngwakọta dị iche iche nke chain integrin nke egosipụtara iche. integrin αalpha X (CD11c) na-agbakọta na integrin αbeta-2 (CD18) n'ime ogige nnabata a maara dị ka CR4 nke nwere ike ijikọta ma mee ka akara ngosi site na ICAM na VCAM-1 na sel endothelial ma nwee ike ịkwado iwepụ iC3b na-ebu sel mba ọzọ.

A na-eji ọgwụ mgbochi N418 eme ihe n'ọtụtụ ebe dị ka ihe nrịbama maka okwu CD11c na mkpụrụ ndụ dendritic (DC), na-adịkarị n'otu n'otu na akara maka CD11b, maka njirimara nke ọkwa mmepe na akụkụ tozuru oke nke ụdị cell a. CD11c na-egosipụta nke ọma na macrophages anụ ahụ, a na-ahụkwa ya na ụfọdụ ụdị sel T arụ ọrụ na intestinal intraepithelial lymphocytes (IEL).

Product Details

aha	violetFluor™ 450 Anti-Mouse CD11c (N418)
Nwamba. Mbanụ.	75-0114
Aha ndị ọzọ	CD11, p150, integrin α?X, Itgax, CR4
Gene ID	16411
mmepụta oyiri	N418
Isotype	Armenian Hamster IgG
Mmeghachi omume	òké
Mmeghachi Omume
format	violetFluor™ 450
ngwa	Cytometry Flow
Nkọwapụta*	Guerriero JL, Ditsworth D, Catanzaro JM, Sabino G, Furie MB, Kew RR, Crawford HC, na Zong WX. 2011. J. Immunol. 186: 3517-3526 . (Immunohistochemistry - anụ ahụ agbakwunyere paraffin) Grewal JS, Pilgrim MJ, Grewal S, Kasman L, Werner P, Bruorton ME, London SD, na London L. 2011. FASEB J. 25:1680-1696. (Immunofluorescence microscopy - anụ ahụ jụrụ oyi) Sadhu C, Ting HJ, Lipsky B, Hensley K, Garcia-Martinez LF, Simon SI, na Staunton DE. 2007. J. Leukoc. Biol. 81: 1395-1403. (igbochi in vitro) Hagnerud, S, Manna PP, Cella M, Stenberg A, Frazier WA, Colonna M, na Oldenborg PA. 2006. J. Immunol. 5772-5778. (Immunofluorescence microscopy - anụ ahụ jụrụ oyi) Finkelman FD, Lees A, Birnbaum R, Gause WC, na Morris SC. 1996. J. Immunol. 157: 1406-1414. (nkwalite na vivo) Huleatt JW na Lefrancois L. 1995. J. Immunol. 154: 5684-5693. (Immunoprecipitation) Metlay JP, Witmer-Pack MD, Agger R, Crowley MT, Lawless D, na Steinman RM. 1990. J. Exp. Med. 171: 1753. (Immunoprecipitation)

Igodo ngwa:FC = cytometry na-asọ; FA = Nyocha ọrụ; ELISA = Enzyme-njikọ Immunosorbent Assay; ICC = Immunocytochemistry; Ọ BỤRỤ na = Immunofluorescence Microscope; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Tissue Frozen; IHC-P = Immunohistochemistry, Tissue agbakwunyere Paraffin; IP = Immunoprecipitation; WB = Ebe Ọdịda Anyanwụ; EM = Electron microscope

*Tonbo Biosciences na-anwale ọgwụ mgbochi ọrịa niile site na cytometry eruba. A na-enye nkọwapụta dịka ihe enyemaka maka ngwa ndị ọzọ nke Tonbo Biosciences na-akwadobeghị. Biko họrọ usoro kwesịrị ekwesị maka ngwa ọ bụla wee lelee ngalaba akụrụngwa na ụzọ maka nkọwa ndị ọzọ gbasara ojiji ngwaahịa ọ bụla dị na mbipụta ndị a.