Yamanaka successfully produced embryonic stem cell-like cells in 2006 by introducing Oct3/4, Sox2, c-Myc, and KLF4 into somatic cells. He gave these cells the term
Mechanical forces and physical signals affect cancer cells, and studying cancer mechanobiology gives hope to new early detection, prognosis evaluation, and therapeutics.
Different tissues and organs in the body have varying levels of matrix stiffness. These differences in stiffness are critical for the proper functioning of cells within their respective tissues.
MSCs are new hope to treat neurodegenerative illnesses such as stroke, traumatic brain injury, Alzheimer’s disease, Parkinson’s disease, and more. Find out how.
Organ-on-a-chip technology allows the cultivation of human liver cells under relevant physiological stresses, allowing deep study of the pathophysiology of liver diseases.
Mesenchymal stem cells (MSCs) are adult multipotent cells that have been shown to have extraordinary anticancer properties, making them a unique option for cancer treatment.
MSC treatment has demonstrated their ability to develop into chondrocytes, healing tissue by producing collagen and matrix, lower inflammation, and provide pain relief for osteoarthritis.
Extracellular vesicles (EVs) are nanoscale lipid bilayer vesicles that are secreted by almost all cell types into the extracellular environment. EVs have a wide
In recent years, chimeric antigen receptor (CAR) T-cell therapy has emerged as one of the most promising immunotherapy for the treatment of cancer. This therapy
Natural killer(NK) cell therapy is a cutting-edge treatment for cancer that is generating excitement in the medical world. This innovative immunotherapy harnesses the power of the body’s own immune system to fight cancer cells. In this article, we’ll explore how NK cell therapy works and what it could mean for patients with cancer.
Cancer immunotherapy has progressed tremendously in recent years, with the emergence of innovative approaches like chimeric antigen receptor (CAR) T-cell therapy and T-cell receptor (TCR)
Adoptive Cell Therapy (ACT) represents a promising approach for the treatment of cancer. It is a process in which immune cells such as T-cells
Spheroids have emerged as powerful tools for advancing biomedical research, with applications ranging from drug screening and toxicity testing to disease modeling and tissue engineering.
Monoclonal antibodies (mAbs) are often used to diagnose and treat many diseases such as cancer. Monoclonal antibodies are produced from immune cells that are clones
Stem cell therapy is one of the most promising approaches in the field of regenerative medicine. It is to promote the repair response of the diseased or injured tissue to restore the lost function. Many diseases can be targeted by cell therapy. These include blood-related diseases, neuronal degenerative diseases, ischemic and cardiovascular disorders, bone and cartilage diseases, wound healing, etc.
iPSCs have a wide range of applications in research and medicine. One of the most promising areas of research is disease modelling.
Despite CAR-T cell therapy’s clinical efficacy, it losses target antigen after therapy. NK cells have a spontaneous cytotoxic activity that is effective even when tumour antigen is downregulated.
Preclinical Animal Models for CAR-T Cell Therapy Chimeric antigen receptor (CAR)-T cell therapy is one of the leading immunotherapies in oncology. Although many clinical trials
Luminescence – or the emission of light from a substance that has not been physically heated – is commonly used in science to provide visualization of entities that are not normally visible to the human eye.
Transforming groundbreaking research into life-changing therapies requires a seamless transition from the lab to the clinic. Scaling up research processes to meet the stringent demands
Human AB Serum, also recognized as AB plasma or AB blood type serum, constitutes a vital blood component obtained from individuals with blood type AB.
Patent protection is a critical form of intellectual property (IP) in the life sciences industry, providing exclusivity to inventors and companies that drive innovation. A
Selecting the right mouse model is a critical decision that can shape the success of your research. With the wide variety of available models, each
Cancer remains a significant global health challenge, placing a heavy burden on healthcare systems worldwide. Low survival rates often stem from the limitations of early
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