Pre-Made HBV-AAV Vectors – Hepatitis B Research

Pre-Made HBV-AAV Vectors – Hepatitis B Research

Pre-Made HBV-AAV Vectors – Hepatitis B Research

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Advance Your Hepatitis B Research with Our Pre-Made AAV-HBV Vectors

Our pre-made AAV-HBV vectors offer a reliable and efficient model for studying hepatitis B virus (HBV) infection and pathogenesis. By delivering a full-length HBV genome into the liver of HBV mice, these vectors enable the establishment of a chronic HBV infection, mimicking human disease.

 

Key Features:

  • Persistent Infection: Induces a long-lasting HBV infection in mice.
  • High-Level Viral Replication: Drives robust viral replication and antigen production.
  • Diverse Applications: Suitable for studying viral pathogenesis, drug discovery, and vaccine development.
  • High-Quality Production: Rigorously tested and quality-controlled to ensure optimal performance.
  • Ready-to-Use: Our pre-made vectors are designed for immediate use, saving you time and effort.

 

AAV-HBV Vector Advantages:

  • Superior Safety Profile:
    • Low probability of genome integration
    • Low immunogenicity
    • High experimental safety
  • Long-Term Gene Expression:
    • Up to 10 years of transgene expression in non-human primates
  • Tissue-Specific Targeting:
    • AAV8 serotype specifically targets the liver, ideal for HBV modeling

 

The PackGene AAV-HBV Vector Difference:

  • Low Empty Shell Rate: Less than 30% empty capsids
  • Mycoplasma-Free: Ensures product purity and reduces contamination risks
  • Comprehensive Quality Control: Rigorous testing and quality inspection reports
  • Low Endotoxin Levels: Minimizes potential inflammatory responses in animal models
  • High Purity and Titer: High-titer preparations (≥1E+13 GC/ml) for efficient gene delivery

 

Accelerate Your Hepatitis B Research

Our pre-made AAV-HBV vectors provide a powerful tool for advancing your understanding of HBV infection and developing novel therapies. By leveraging the advantages of AAV technology, you can achieve reliable and reproducible results.

 

Contact us today to discuss your research goals and explore our range of pre-made and custom AAV-HBV vectors.

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Product Specifications

Promoter type

Catalog No.

Promoter and Gene

EF1a AAV-DR031 ssAAV.EF1a- hM3Dq- mCherry- WP RE
AAV-DR032 ssAAV.EF1a- DIO-HA- hM3D(Gq)- IRES- mCitrine
AAV-DR034 ssAAV.EF1a- HA- hM3D(Gq)- mCherry
AAV-DR035 ssAAV.EF1a- hM3D(Gq)- mCherry
AAV-DR036 ssAAV.EF1a- DIO- hM3D(Gq)- mCherry
AAV-DR038 ssAAV.EF1a- DIO- rM3D(Gs)- mCherry
AAV-DR039 ssAAV.EF1a- DIO- hM4D(Gi)- mCherry
AAV-DR0310 ssAAV.EF1a- HA- hM4D(Gi)- mCherry
AAV-DR0311 ssAAV.EF1a-DIO- mCherry
AAV-DR0312 ssAAV.EF1a- dF-HA- KORD- IRES- mCitrine
AAV-DR0313 ssAAV.EF1a-HA-KORD-IRES-mCitrine
AAV-DR0314 ssAAV.EF1a-DIO-GFP
mOXT AAV-DR391 ssAAV.mOXT-hM3Dq-mCherry-WPRE
AAV-DR392 ssAAV.mOXT-DIO-HA-hM3D(Gq)-IRES-mCitrine
AAV-DR393 ssAAV.mOXT-HA-hM3D(Gq)-IRES-mCitrine
AAV-DR394 ssAAV.mOXT-HA-hM3D(Gq)-mCherry
AAV-DR396 ssAAV.mOXT-DIO-hM3D(Gq)-mCherry
AAV-DR398 ssAAV.mOXT-DIO-rM3D(Gs)-mCherry
AAV-DR3912 ssAAV.mOXT-dF-HA-KORD-IRES-mCitrine
AAV-DR3913 ssAAV.mOXT-HA-KORD-IRES-mCitrine
hSyn AAV-DR101 ssAAV.hSyn- hM3Dq-mCherry-WPRE
AAV-DR102 ssAAV.hSyn- DIO- HA- hM3D(Gq)- IRES- mCitrine
AAV-DR103 ssAAV.hSyn- HA- hM3D(Gq)- IRES- mCitrine
AAV-DR104 ssAAV.hSyn- HA- hM3D(Gq)- mCherry
AAV-DR106 ssAAV.hSyn- DIO- hM3D(Gq)- mCherry
AAV-DR108 ssAAV.hSyn-DIO-rM3D(Gs)-mCherry
AAV-DR109 ssAAV.hSyn-DIO-hM4D(Gi)-mCherry
AAV-DR1011 ssAAV.hSyn- DIO- mCherry
AAV-DR1012 ssAAV.hSyn-dF-HA-KORD-IRES-mCitrine
AAV-DR1014 ssAAV.hSyn.DIO.EGFP.WPRE.bGHpA
AAV-DR1015 ssAAV.hSyn.DIO.EGFP.WPRE.SV40pA
CaMKlla AAV-DR131 ssAAV.CaMKlla- hM3Dq- mCherry- WPRE
AAV-DR133 ssAAV.CaMKIIa-HA-hM3D(Gq)-IRES-mCitrine
AAV-DR134 ssAAV.CaMKIIa-HA-hM3D(Gq)-mCherry
AAV-DR135 ssAAV.CaMKlla- hM3D(Gq)- mCherry
AAV-DR136 ssAAV.CaMKlla- DIO- hM3D(Gq)- mCherry
AAV-DR138 ssAAV.CaMKlla- DIO- rM3D(Gs)-mCherry
AAV-DR139 ssAAV.CaMKlla- DIO- hM4D(Gi)-mCherry
AAV-DR1310 ssAAV.CaMKlla- HA- hM4D(Gi)- mCherry

Case Study