Illuminate Your Neuroscience Research with Pre-made Optogenetics AAV Vectors

Our pre-made optogenetics AAV vectors offer a powerful tool for precise control of neuronal activity. By expressing light-sensitive ion channels, you can manipulate neuronal firing patterns with millisecond precision.

How It Works:

1. Vector Delivery: AAV vectors carrying genes for light-sensitive ion channels, such as Channelrhodopsin-2 (ChR2) or Halorhodopsin (NpHR), are delivered to specific neurons.
2. Protein Expression: The AAV vectors express the ion channels within the targeted neurons.
3. Optical Stimulation: Fiber optics are used to deliver light pulses to the neurons expressing the ion channels.
4. Neural Activity Modulation: The light-activated ion channels respond to the light pulses, causing changes in membrane potential and ultimately altering neuronal activity.
   1. ChR2: Activates neurons upon exposure to blue light.
   2. NpHR: Inhibits neurons upon exposure to yellow light.

Key Applications:

• Circuit Mapping: Identify neural circuits involved in specific behaviors and cognitive functions.
• Neuromodulation: Manipulate neural activity to study the effects on behavior and physiology.
• Disease Modeling: Model neurological disorders and identify potential therapeutic targets.
• Drug Discovery: Screen for compounds that modulate neuronal activity.

Simplify Your Neuroscience Research

Our pre-made optogenetics AAV vectors are designed to simplify your neuroscience research. By eliminating the need for complex vector construction, you can focus on your core research objectives.

Contact us today to discuss your research goals and explore our range of pre-made and custom optogenetics AAV vectors.

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