Pre-Made AAV Control Vectors

Pre-Made AAV Control Vectors

Pre-Made AAV Control Vectors

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Choosing the Right Pre-Made AAV Control Vectors

When designing your gene therapy experiment, selecting the appropriate AAV control is crucial for accurate data interpretation. A well-chosen control can significantly enhance the reliability and validity of your research.

 

Key Factors to Consider:

  1. AAV Serotype:

    1. Tissue Tropism: Different serotypes exhibit distinct tissue tropisms, influencing gene expression patterns.
    2. Immune Response: Consider the potential immunogenicity of the serotype, as it can impact vector efficacy and safety.
  2. Promoter Strength and Specificity:

    1. Tissue-Specific Promoters: Target gene expression to specific cell types.
    2. Constitutive Promoters: Drive continuous gene expression.
  3. Reporter Gene:

    1. Fluorescent Proteins: Visualize gene expression patterns in live cells and tissues.
    2. Luminescent Proteins: Quantify gene expression levels.

 

Our Pre-Made AAV Control Vectors: A Tailored Solution

Packgene offers a diverse range of pre-made AAV control vectors to meet your specific research needs. Their

Our products are designed to:

  • Validate Gene Delivery: Assess the efficiency and specificity of your AAV vectors.
  • Monitor Transgene Expression: Track gene expression levels over time.
  • Evaluate Immune Responses: Assess the immunogenicity of your AAV vectors.

 

 

Packgene Pre-made AAV Control Vector Advantages:

  • Wide Serotype and Strand Options: Available in a range of serotypes and both single-stranded and double-stranded formats.
  • High Titer: Exceeding 1E+13 GC/ml for efficient gene delivery.
  • Versatile Promoters: Choose from a variety of promoters to match your experimental needs.
  • Rapid Expression: Double-stranded AAVs offer 6-15 times faster expression.
  • Stable and Reliable Performance: Consistent results for reliable data interpretation.

 

This product is applicable for worldwide delivery.

 

Need a Custom Control Vector?

If you have specific requirements, our custom vector design and production services can provide tailored solutions to meet your exact needs.

 

Contact us today to discuss your research goals and explore our range of pre-made and custom AAV control vectors.

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Product Specifications

Purified Empty AAV Capsid Particles

Our empty AAV particles created using only essential components for AAV replication provides a versatile tool for a variety of research applications, including:

  • Normalizing Transduction Efficiency: Use as a control to normalize transduction efficiency in gene therapy experiments.
  • Studying Viral Entry and Trafficking: Investigate the mechanisms of AAV entry and intracellular trafficking.
  • Developing Novel AAV-Based Therapeutics: Engineer empty capsids for targeted drug delivery or as immunotherapeutic agents.

 

These EMP AAV capsid particles are completely empty capsids that are devoid of any genetic material and therapeutic transgene.

 

Type Catalog No. Promoter and Gene Serotype Concentration QC
Empty AAV particles AAVEC001 Non AAV2, AAV5, AAV8, AAV9 1E13 VP/mL Endotoxin by LAL<10EU/mL Purity by SDS-PAGE Capsid titer by ELISA

 

 

A Comprehensive Range of AAV Control Vectors

Our pre-made AAV control vectors offer a reliable and efficient solution for your gene therapy, gene editing, gene regulation, vaccine development, and drug discovery research. Choose from a variety of serotypes, promoters, and reporter genes to suit your specific research needs.

 

Popular Control Vector Combinations:

  • Serotype 5 (AAV5): A versatile serotype with broad tissue tropism.
    • CAG Promoter: A strong, constitutive promoter for ubiquitous gene expression.
    • eGFP or mCherry Reporter: Brightly fluorescent proteins for easy visualization.
  • Serotype 8 (AAV8): A potent serotype with high transduction efficiency in various tissues.
    • CBh Promoter: A strong, constitutive promoter for efficient gene expression.
    • Luciferase Reporter: A sensitive reporter for quantitative analysis.

 

Type Catalog No. Promoter and Gene
No reporter AAV AAV-EA020 ssAAV.CAG.WPRE.SV40pA
AAV-EC020 scAAV.CAG.WPRE.SV40pA
AAV-EA040 ssAAV.CMV.WPRE.SV40pA
Fluorescence AAV-EA021 ssAAV.CAG.EGFP.WPRE.SV40pA
AAV-EC021 scAAV.CAG.EGFP.WPRE.SV40pA
AAV-EA041 ssAAV.CMV.EGFP.WPRE.SV40pA
AAV-EC041 scAAV.CMV.EGFP.WPRE.SV40pA
AAV-EA022 ssAAV.CAG.mCherry.WPRE.SV40pA
AAV-EC022 scAAV.CAG.mCherry.WPRE.SV40pA
AAV-EA042 ssAAV.CMV.mCherry.WPRE.SV40pA
AAV-C-11723 scAAV.CMV.mCherry.WPRE.SV40pA
AAV-EB041 ssAAV.CMV.EGFP.PA48
AAV-EA191 ssAAV.CBh.EGFP.WPRE.SV40pA
AAV-EA031 ssAAV.EF1a.EGFP.WPREs.SV40pA
AAV-EA051B ssAAV.TBG (669p).EGFP.WPRE.SV40pA
AAV-EA101 ssAAV.hSyn.EGFP.WPREs.SV40pA
AAV-EA171 ssAAV.hGFAPS.EGFP.WPREs.SV40pA
AAV-EA411 ssAAV.miniCMV.EGFP.WPRE.SV40pA
AAV-EA011 ssAAV.EFS.EGFP.WPRE.SV40pA
AAV-EA042 ssAAV.CMV.mCherry.WPRE.SV40pA
AAV-EA181 ssAAV.CTNT.ZsGreen.WPRE.SV40pA
AAV-EA591 ssAAV.UBC.EGFP.WPRE.SV40pA
AAV-EA361 ssAAV.Tie1.EGFP.WPRE.SV40pA
AAV-EC011 scAAV.EFS.EGFP.WPRE.SV40pA
AAV-EA611 ssAAV.mSP-C promoter.EGFP.WPRE.SV40pA
AAV-EA511 ssAAV.periostin.EGFP.WPRE.SV40pA
AAV-EA501 ssAAV.Iba1.EGFP.WPRE.SV40pA
AAV-EB361 ssAAV.Tie1.EGFP.PA48
AAV-EA621 ssAAV.mRPE65.EGFP.WPRE.SV40pA
AAV-EA461 ssAAV.GfaABC1D.EGFP.WPRE.SV40pA
AAV-EA491 ssAAV.hICAM2.EGFP.WPRE.SV40pA
AAV-EA102 ssAAV.hSyn.mCherry.WPRE.SV40pA
AAV-EA071 ssAAV.Rat Insulin.EGFP.WPRE.SV40pA
AAV-EC028 scAAV.CAG.GLuc.WPRE.SV40pA
AAV-EA441 ssAAV.EnSM22α.EGFP.WPRE.SV40pA
AAV-EC051V scAAV.TBG.EGFP.WPRE.SV40pA
AAV-EC101 scAAV.hSyn.EGFP.WPRE.SV40pA
AAV-EA391B ssAAV.MBP(1.9kb).EGFP.WPRE.SV40pA
AAV-EA631 ssAAV.hBEST1.EGFP.WPRE.SV40pA
AAV-EA026 ssAAV.CAG.EYFP.WPRE.SV40pA
AAV-EA182 ssAAV.CTNT.EGFP.WPREs.SV40pA
AAV-EA601 ssAAV.HCRApoE hAAT.EGFP.WPRE.SV40pA
AAV-EA531 ssAAV.mALB.EGFP.WPRE.SV40pA
AAV-EC181 scAAV.CTNT.ZsGreen.WPRE.SV40pA
AAV-C-11592 ssAAV.SMMHC.EGFP.WPRE.SV40pA
AAV-C-11307 scAAV.miniCMV.mCherry.WPREs.SV40pA
AAV-C-3199 ssAAV.CAG.EGFP.NLS.WPRE.SV40pA
Luminesence AAV-EA029 ssAAV.CAG.Fluc.WPRE.SV40pA
AAV-EA043 ssAAV.CMV.Fluc.WPRE.SV40pA
AAV-EC028 scAAV.CAG.Gluc.WPRE.SV40pA
shRNA AAV-XN09 scAAV.U6.NCshRNA.CMV.EGFP.WPRE
AAV-C-10987 scAAV.U6.NCshRNA-2.CAG.EGFP.WPRE.SV40pA