Targeted therapy for cancer is a treatment modality at the cellular molecular level that targets a known cancer-causing site. Common targeted drugs include small molecule drugs and monoclonal antibodies. Monoclonal antibodies have higher selectivity but are large molecule proteins, which are difficult to enter cells, and their targets are often limited to the cell surface; small molecule drugs are advantageous for targeting molecules inside tumor cells since they are small enough to easily enter tumor cells and directly target the molecules inside. With high specificity and less toxic side effects, targeted drugs have remarkable therapeutic efficacy on a variety of malignant tumors. They have become the new mainstream antitumor drugs in the last decade.

TargetMol collected 121 tumor-targeted drugs and formed the Targeted Therapy Drug Library, a powerful tool in oncotherapy research.