Deep Delivery System (DDS) Retinol

Deep Delivery System (DDS) Retinol

Deep Delivery System (DDS) Retinol

Retinyl Palmitate encapsulated in our VEGAN DDS system to protect retinol from degradation or oxidation and delivered into the deepest layers of the epidermis with an efficiency 20 times greater (> 2000 %) than the free active.

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Retinyl Palmitate is one of the most reliable ways to provide the skin with vitamin A. It stimulates the production of hyaluronic acid, collagen and elastin which improves skin strength and elasticity being the reason why it is considered one of the most potent anti-aging active ingredients.

It also accelerates the cell regeneration process, improving the general appearance and texture of the skin and minimising the pore size. For this reason, together with its ability to regulate sebum production, it is commonly found in acne treatment products. Furthermore, it represses the production of melanin thereby reducing the number and intensity of skin blemishes.

What is DDS Retinol?

Retinyl Palmitate encapsulated in our VEGAN DDS system to protect retinol from degradation or oxidation and delivered into the deepest layers of the epidermis with an efficiency 20 times greater (> 2000 %) than the free active.

Our DDS retinol is formulated to be 100% vegan friendly and free from animal origin ingredients.

ACTIVE INGREDIENT PROPERTIES of DDS-RETINOL

  • Stimulates the production of collagen, elastin and hyaluronic acid.
  • Acts as an antioxidant and cell regenerator.
  • Minimises pore size and prevents hyperkeratinisation.
  • Regulates the production of sebum.
  • Represses melanogenesis

BENEFITS OF THE ENCAPSULATION DDS TECHNOLOGY

  • Protects the retinyl palmitate against degradation.
  • Maximum delivery of the active ingredient to the deep skin levels.
  • Multiplies efficiency without exceeding the SCCS recommended dosage.
  • Gradual delivery for longer lasting effect.
  • Increases the bioavailability of the active ingredient.
  • Allows the formulation of retinyl palmitate in aqueous bases.
  • Avoids colour changes in the cosmetic product

PROPERTY CHARACETRISTICS of DDS-RETINOL

  • Retinyl palmitate encapsulated at 3% in the INdermal DDS system.
  • +1153% delivery compared to non-encapsulated active ingredient.
  • Pale yellow coloured liquid.
  • Biomimetic nanovesicle with high moisturising action and restorative.

Efficiency of DDS-Retinol

The soluble collagen content was calculated using a soluble collagen assay kit by Biocolor Limited (Car­rickfergus, UK). The collagen test is a dye binding method for the purpose of analysing soluble collagens in acid and pepsin. The test can evaluate the amount of recently synthesised collagen produced during rapid periods of growth and development. The values are expressed in μg / mg of hOSEC.

DDS Retinol efficacy on ellastin growth after treatment on stressed skin explant

The results show that vegan DDS-Retinyl & DDS Retinyl generate new elastic and could generate a restructuring of the skin tissue in stressed skin explants under test conditions.

  • At equal concentration levels of Retinyl palmitate, the DDS-Retinol and Vegan DDS-Retinol prod­ucts are much more effective than Retinyl palmitate in free form, recovering the amount of lost collagen and elastin to levels similar to those found in natural skin before undergoing aging.
  • Vegan DDS-Retinol product act immediately as evidenced after eleven days by a large recovery (98% average) of the elastin and collagen lost through the enforced aging process whilst the free active ingredient would need a much longer application period.